Kaname & Ruka

This B-class or Noble vampire is in love, maybe since she first met him or she started having feelings toward the pureblood when she entered Cross Academy following the late. However Kaname never met her feelings and barely makes note of them. Ruka however do not lose her hopes and tried to make him fall in her arms in past occasions.

It is important to say that Kaname once drank her blood out of deseperation so he could make Yuki realize what he truly was and at the same time break all her expectations so he wouldn't feel tempted himself to press his own fangs on Yuki's throat. At that time Ruka felt overjoyed thinking Kaname was choosing her but soon after came the realization.

Ruka is one of the many collateral-effects Kaname made following his plans still, she somewhat oblige and stay by the pureblood side knowing she has little to no chance to actually get something more than a friendship. This fact makes their relationship one of the sadest ones in Vampire Knight although it is also satisfying to not see a character like her degenerate and wishing bad to fall on the pureblood.